在中成药制剂中,大黄的应用很广泛。长期来,大黄品质优劣的鉴别仍以传统的外观检查为主,但其鉴别结果常不能准确地反映生药内在质量的优劣程度。为了保证中成药制剂的质量,确有必要应用现代的科学方法对大黄进行质量分析,逐步建立其品质标志。大黄生药中蒽醌类成分的含量测定一般多利用蒽醌类化合物在碱性溶液中呈红色的反应进行比色定量。因游离蒽醌的生理活性不强,而蒽醌甙类具有药效,所以应测定结合蒽醌的含量。王慕邹等与中国医学科学 In the preparation of proprietary Chinese medicines, rhubarb is widely used. In the long run, the identification of the quality of rhubarb is still based on traditional visual inspection, but its identification results often do not accurately reflect the quality of the inherent quality of crude drugs. In order to ensure the quality of proprietary Chinese medicine preparations, it is indeed necessary to apply modern scientific methods to quality analysis of rhubarb and gradually establish its quality mark. The determination of the content of anthraquinones in rhubarb crude drugs is generally performed by colorimetric quantification using the reaction of quinones in red in alkaline solution. Since the physiological activity of free scorpion is not strong, and stilbenes have efficacy, the content of conjugated yttrium should be determined. Wang Mu-Zou et al. and Chinese Medical Science