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目的探讨布地奈德与沙丁胺醇联合雾化吸入治疗毛细支气管炎的临床疗效。方法将80例毛细支气管炎患儿随机分为治疗组45例,对照组35例。两组均给予常规综合治疗,治疗组在常规治疗基础上加用布地奈德、沙丁胺醇雾化吸入治疗,对照组在常规治疗基础上加用病毒唑、地塞米松、α-糜蛋白酶雾化吸入治疗。结果治疗组有效率明显高于对照组,气促缓解天数、哮鸣音消失天数及住院时间明显短于对照组,统计学差异有显著性意义(p<0.01)。结论布地奈德与沙丁胺醇联合雾化吸入治疗毛细支气管炎可明显缩短疗程,提高治疗有效率。
Objective To investigate the clinical efficacy of budesonide combined with albuterol inhalation in the treatment of bronchiolitis. Methods Eighty children with bronchiolitis were randomly divided into treatment group (45 cases) and control group (35 cases). The two groups were given conventional comprehensive treatment, the treatment group on the basis of conventional treatment with budesonide, salbutamol inhalation therapy, the control group on the basis of routine treatment plus ribavirin, dexamethasone, α-chymotrypsin inhalation treatment. Results The effective rate of the treatment group was significantly higher than that of the control group. The number of days of relief, days of wheeze disappearance and hospital stay were significantly shorter than those of the control group, with significant difference (p <0.01). Conclusions The combination of budesonide and albuterol inhalation for the treatment of bronchiolitis can significantly shorten the course of treatment and improve the treatment efficiency.