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布新洛尔(Bucindolol)为一强效非选择性β阻滞剂,兼有直接扩张血管作用,可降低心率、血压和体循环血管阻力。 23例特发性扩张型心肌病,心功能Ⅱ～Ⅲ级,随机口服布新洛尔(13例)或安慰剂。布新洛尔起始量12.5mg每12小时1次,
Bucindolol is a potent, nonselective beta-blocker that directly dilates blood vessels and decreases heart rate, blood pressure, and systemic vascular resistance. 23 cases of idiopathic dilated cardiomyopathy, cardiac function Ⅱ ~ Ⅲ grade, random oral bupivacaol (13 cases) or placebo. The initial amount of clothinolol 12.5mg once every 12 hours,