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目的探讨高尿酸血症与代谢综合征及其各组分的关系。方法采用分层整群抽样方法,对哈尔滨市4043例参加健康体检的人群进行体格(身高、体重、血压)和生化(空腹血糖、血尿酸、甘油三酯、总胆固醇、高密度脂蛋白胆固醇)检查。运用SPSS 20.0软件进行t检验、χ2检验和Logistic回归模型分析高尿酸血症的危险因素。结果高尿酸血症、代谢综合征和高尿酸血症合并代谢综合征患病率分别为18.91%、17.90%和5.58%;高尿酸血症患病率随代谢综合征组分数量的增多而升高(P<0.05)。多因素Logistic回归分析表明,代谢综合征组分中的超重或肥胖、血脂代谢紊乱为高尿酸血症的独立危险因素(OR>1,P<0.05)。结论高尿酸血症与代谢综合征之间关系密切,超重或肥胖和血脂代谢紊乱是高尿酸血症的独立危险因素。
Objective To investigate the relationship between hyperuricemia and metabolic syndrome and its components. Methods The stratified cluster sampling method was used to study the physical (height, weight, blood pressure) and biochemical (fasting blood glucose, blood uric acid, triglyceride, total cholesterol and high density lipoprotein cholesterol) levels in 4043 people in Harbin. an examination. SPSS 20.0 software was used for t test, χ2 test and Logistic regression model to analyze the risk factors of hyperuricemia. Results The prevalences of hyperuricemia, metabolic syndrome and hyperuricemia with metabolic syndrome were 18.91%, 17.90% and 5.58% respectively. The prevalence of hyperuricemia was increased with the increase of the number of metabolic syndrome components High (P <0.05). Multivariate logistic regression analysis showed that overweight or obesity and dyslipidemia in metabolic syndrome were independent risk factors for hyperuricemia (OR> 1, P <0.05). Conclusion Hyperuricemia is closely related to metabolic syndrome. Overweight or obesity and dyslipidemia are independent risk factors of hyperuricemia.