目的 :考察不同装量的静脉用氯化钠注射液中不溶性微粒的变化 ,保障临床用药安全。方法 :用注射液微粒分析仪分别检查不同装量的氯化钠注射液中的不溶性微粒。结果 :经反复抽取过的大体积包装的注射液的剩余液体中不溶性微粒有 5 0 %超出了控制标准。结论 :在溶解干粉针剂或稀释针剂作静脉注射时 ,应使用小装量的氯化钠注射液。 OBJECTIVE: To investigate the changes of insoluble particles in intravenous sodium chloride injection of different doses to ensure the safety of clinical medication. Methods: The injection of particle analyzer were examined in different doses of sodium chloride injection of insoluble particles. RESULTS: Fifty percent of the insoluble particles in the remaining liquid that had been drawn back into the large volume of packed injection were outside the control criteria. CONCLUSIONS: Small doses of sodium chloride injection should be used when intravenous injection of dissolved dry powder or diluted injection.