自1945年Brotzu发现头孢菌素以来,对此类抗生素的开发和研究日益进步,特别是六十年代以来,新品种不断出现,如今,第四代头孢菌素业已问世。近几年来,世界各国对第三代头孢菌素的基础和临床研究的报告颇多,这一代头孢菌素的特点是:对β-内酰胺酶高度稳定;对肾脏基本无毒性; Since cephalosporin was discovered by Brotzu in 1945, the development and research of such antibiotics has been on the rise. Especially since the 1960s, new varieties have emerged. Now, the fourth generation of cephalosporins has come out. In recent years, many countries in the world report on the third generation cephalosporins basic and clinical research, this generation of cephalosporins is characterized by: highly stable β-lactamase; basic non-toxic to the kidneys;