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目的调查基层医院高甘油三脂血症(triglyceride,TG)患者使用非诺贝特类降脂药的情况,分析各种因素对调脂药物使用的影响。方法通过对高甘油三脂血症病人共6375例的电话回访、查门诊日志、住院病历等方式,确认患者使用非诺贝特情况,分析各种因素对调脂药物使用的影响。结果本组6375例高TG患者中,单纯高TG患者1849例占29.00%(1849/6375),混合高脂血症患者(以高甘油三脂升高为主)4526例占71.00%(4526/6375),使用非诺贝特类降脂药3285例占51.53%(3285/6375),错误使用他汀类降脂药例数2038例占31.96%(2038/6375)。结论通过本院调查研究发现,在基层医院很多高甘油三脂血症患者未得到有效、正确、合理、及时的调脂治疗,未得到正确的临床指导,未引起患者及广大基层医院医生们的重视,因此可能会造成患者进一步损害,应大力普及和推广新的调脂治疗指南,加强医生培训,加大宣传力度,做到及时引导,正确、有效治疗,促进全面调脂治疗达标。
Objective To investigate the use of fenofibrate-based lipid-lowering drugs in patients with triglyceride (TG) in primary hospitals and analyze the influence of various factors on the use of lipid-lowering drugs. Methods A total of 6375 cases of hypertriglyceridemia in patients with telephone interview, check the outpatient log, inpatient records and other ways to confirm the use of fenofibrate in patients with various factors on the use of lipid-lowering drugs. Results Among the 6375 hypertensive patients with high TG, 1849 cases (1849/6375) were hypertensive patients and 4526 cases (71.5%) were patients with mixed hyperlipemia (mainly hypertriglyceridemia) 6375). 3285 cases of fenofibrate lipid-lowering drugs accounted for 51.53% (3285/6375). Misdirected statin lipid-lowering drugs accounted for 31.96% (2038/6375) in 2038 cases. Conclusions Our hospital found that many hypertriglyceridemia patients in primary hospitals did not receive effective, correct, reasonable and timely lipid-lowering treatment, did not get the correct clinical guidance, did not cause patients and the majority of primary hospital doctors Therefore, it may cause further damage to patients. We should vigorously popularize and popularize new guidelines for lipid-lowering treatment, strengthen training for doctors and step up publicity so as to timely guide correct and effective treatment and promote full-scale lipid-lowering treatment.