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目的总结应用甲钴胺联合α硫辛酸治疗老年糖尿病周围神经病变36例体会。方法将72例老年糖尿病周围神经病变患者均维持饮食、运动、有效控制血糖等治疗基础上分为:对照组36例:应用维生素B6,维生素B12治疗;观察组36例:应用甲钴胺联合α硫辛酸治疗。治疗4周后,观察2组神经症状改善效果。结果对照组症状明显改善9例,好转20例,总有效率80.6%;对照组症状明显改善6例,症状好转16例,总有效率61.1%。观察组有效率明显高于对照组。结论在饮食、运动、有效控制血糖等基础治疗上,应用甲钴胺联合α硫辛酸治疗老年糖尿病周围神经病变,改善症状明显,疗效肯定。
Objective To summarize 36 cases of senile diabetic peripheral neuropathy treated with mecobalamin and alpha lipoic acid. Methods 72 elderly diabetic peripheral neuropathy patients were maintained diet, exercise, blood glucose control and other treatments are divided into: the control group of 36 patients: the application of vitamin B6, vitamin B12 treatment; observation group of 36 patients: the application of mecobalamin combined with α Lipoic acid therapy. After 4 weeks of treatment, two groups of neurological symptoms were observed. Results The symptoms of the control group were significantly improved in 9 cases, improved in 20 cases, the total effective rate was 80.6%. In the control group, the symptoms were significantly improved in 6 cases and the symptoms improved in 16 cases. The total effective rate was 61.1%. Observation group, the effective rate was significantly higher than the control group. Conclusions Mecobalamin and α-lipoic acid are effective in treating diabetic peripheral neuropathy in elderly patients with diet, exercise and effective control of blood glucose.