应用选择性地作用于突触前膜的β-BGT,川楝素,β-AgTx以及选择性地作用于AChR的α-BGT,能与人骨骼肌提取的混合受体粗提液中各自的靶蛋白结合的特性,以ABC-ELISA方法检测了43例正常人和43例重症肌无力病人血清中的相应抗体。结果发现重症肌无力病人血清中存在抗突触膜上述数种蛋白成分的相应抗体。该结果提示某些重症肌无力病人的神经肌肉接头处存在多重免疫损伤。 Application of β-BGT, toosendanin, β-AgTx, and α-BGT that selectively act on AChR, acting selectively on the presynaptic membrane, can be combined with each of the According to the characteristics of target protein binding, the corresponding antibodies in the serum of 43 normal subjects and 43 myasthenia gravis patients were detected by ABC-ELISA. The results showed that there is anti-synaptic membrane antibodies in patients with myasthenia gravis the above several protein components of the corresponding antibodies. The results suggest that there are multiple immune damage at the neuromuscular junction in some patients with myasthenia gravis.