1例57岁女性患者因左股骨颈骨折行髋关节置换术。术后17 d患者出现发热,20 d血培养示沃氏葡萄球菌阳性。给予替考拉宁0.4 g入0.9%氯化钠100 ml、1次/12 h静脉滴注,头孢唑肟2.0 g、2次/d口服。第4天患者双侧小腿出现瘀斑,血小板计数由249×109/L降至25×109/L。停用替考拉宁,头孢唑肟继续使用,第7天血小板计数恢复至104×109/L,瘀斑基本消退。 A 57-year-old female patient underwent hip arthroplasty for left femoral neck fracture. Hemorrhages occurred on day 17 after surgery and were positive for Staphylococcus aureus after 20 days of blood culture. To give teicoplanin 0.4 g into 0.9% sodium chloride 100 ml, 1/12 h intravenous infusion, ceftizoxime 2.0 g, 2 times / d orally. On the 4th day, the bruises appeared on the bilateral lower legs, and the platelet count decreased from 249 × 109 / L to 25 × 109 / L. Decommissioned teicoplanin, ceftizoxime continue to use, on the seventh day platelet count returned to 104 × 109 / L, eczema basically subsided.