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目的:对2811例婴幼儿腹泻患者进行粪便轮状病毒抗原检测,分析其发病规律。方法:利用胶体金法快速诊断试剂盒检测婴幼儿腹泻患者粪便轮状病毒抗原,并对结果进行统计分析。结果:2811例婴幼儿腹泻患者送检标本中检测到645株轮状病毒抗原阳性,阳性率为22.95%;6月～2岁幼儿是轮状病毒感染的高发年龄段,检测阳性率为55.65%;本地区轮状病毒腹泻发病的高峰季节是10月～2月。结论:轮状病毒感染是导致婴幼儿腹泻的主要原因之一,临床医生应重视腹泻婴幼儿病人轮状病毒的检测以明确诊断,防止滥用抗生素而导致肠道菌群失调。胶体金法检测轮状病毒具有简单、快速、特异性高的特点,适合在各级医疗单位尤其是基层单位的推广应用。
Objective: To detect stool rotavirus antigen in 2811 infants with diarrhea and analyze its pathogenesis. Methods: The stool rotavirus antigens in infants with diarrhea were detected by the colloidal gold rapid diagnostic kit, and the results were statistically analyzed. Results: A total of 645 rotavirus positive samples were detected in 2811 cases of infantile diarrhea, with a positive rate of 22.95%. June-2-year-old children were the highest incidence of rotavirus infection with a positive rate of 55.65% ; The peak season of rotavirus diarrhea in this area is from October to February. Conclusion: Rotavirus infection is one of the major causes of diarrhea in infants and young children. Clinicians should pay attention to the detection of rotavirus in infants and young children with diarrhea to confirm the diagnosis and prevent the abuse of antibiotics and lead to the imbalance of intestinal microflora. Colloidal gold detection of rotavirus with a simple, fast, high specificity, suitable for all levels of medical units, especially the promotion and application of grassroots units.