视网膜母细胞瘤(RB)是一种多在婴幼儿发病的眼内恶性肿瘤。1963年Lete报道1例RB患者伴有1条D纽染色体长臂的部分缺失。自此,关于RB的细胞遗传学研究引起了许多学者的重视。已积累的材料约3～5%的忠者伴13q-。13号染色体以外的非随机变化也时有发现。作者发现1例RB患者伴有Y染色体长臂部分 Retinoblastoma (RB) is an intraocular malignancy that occurs mostly in infants and young children. In 1963, Lete reported a partial deletion of one long arm of the D chromosome in one patient with RB. Since then, the research on the cytogenetics of RB has attracted the attention of many scholars. The accumulated material is about 3 ~ 5% loyalty with 13q-. Non-random changes other than chromosome 13 have also been found. The authors found 1 RB patients with Y chromosome long arm