目的:探讨早期卵巢支持-间质细胞瘤(SLCT)的临床特征、诊疗及预后。方法:回顾分析福建省妇幼保健近年内确诊的5例早期SLCT患者的临床资料,分析其临床特征、诊疗及预后。结果:5例SLCT患者均为Ia期;因不孕症确诊3例,因继发性闭经、附件区肿物确诊1例,因绝经后发现附件区肿物确诊1例。血清睾酮水平在术后1周均恢复正常,其中4例术后睾酮水平均较术前下降10倍以上;肿物均为表面光滑、包膜完整的单侧性瘤体,均无腹水征;高、中、低分化者各1例,中-低分化者2例;均行手术治疗,低分化者辅以BEP方案化疗;预后良好,术后2例自然受孕。结论:SLCT极易误诊、漏诊;血清睾酮水平长期持续异常升高是部分早期SLCT患者的重要临床特征;SLCT与不孕症存在关联,尽早诊治可有助于提高孕育机率。 Objective: To investigate the clinical features, diagnosis and prognosis of early ovarian support-stromal cell tumor (SLCT). Methods: The clinical data of 5 cases of early stage SLCT confirmed by MCH in Fujian Province in recent years were retrospectively analyzed, and their clinical characteristics, diagnosis and treatment and prognosis were analyzed. Results: 5 cases of SLCT patients were stage Ia; 3 cases of infertility, 1 case of secondary amenorrhea due to infertility and 1 case of tumor in the annexed area. Serum testosterone levels returned to normal at 1 week after operation, and the postoperative testosterone levels in 4 of them were more than 10 times lower than those before operation. The tumors were smooth and covered with unilateral ascites. There were 1 case of high, medium and poorly differentiated, 2 cases of moderately-poorly differentiated. All patients underwent surgical treatment and poorly differentiated with BEP regimen. The prognosis was good and 2 cases were naturally conceived. Conclusion: SLCT can be easily misdiagnosed and missed. Long-term persistent abnormal serum testosterone level is an important clinical feature in some early SLCT patients. SLCT is associated with infertility. Early diagnosis and treatment may help to increase the chance of pregnancy.