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目的 探讨体外受精-胚胎移植(in vitro fertilization-embryo transfer,IVF-ET)过程中胚移植后4天血清孕激素(progesterone,P)与IVF-ET结局的关系.方法 将研究对象根据妊娠结局分为妊娠组和非妊娠组,比较两组P差异;将研究对象根据P值分成3组(A组:P＜50nmol/L,B组:50nmol/L＜P＜120nmol/L,C组:P＞120nmol/L)分析3组间着床率、临床妊娠率、早期自然流产率差异.结果 妊娠组与非妊娠组P差异无统计学意义(P＞0.05),三组间着床率、临床妊娠率差异无统计学意义(P＞0.05),B组早期自然流产率较A组和C组显著下降,差异有统计学意义(P＜0.05).结论 胚胎移植后4天血清P水平与临床妊娠率无显著相关性,但P在50-120nmol/L之间早期自然流产率最低.“,”Objective:To investigate the influence of serum progesterone to pregnancy outcome of IVF-ET on the fourth day after embryo transfer.Methods:According to the outcome of pregnancy,the patients were divided into pregnancy group and non-pregnancy group,then compared the difference of P between the two groups;According to the serum P,the patients were divided into three groups (A group:P＜50nmol/L,B group:50 nmol/L＜P＜120 nmol/L,C group:P＞120 nmol/L),and reviewed focusing on the implantation rate,clinical pregnancy rate and early spontaneous abortion rate.Results:There were no statistical difference in the P between the pregnancy group and the non-pregnancy group (P＞0.05).There were no statistical difference in the implantation rate,the clinical pregnancy rate among the three groups (P＞0.05).The early spontaneous abortion rate of B group was significantly lower than that of A group and C group,the difference was statistically significant (P＜ 0.05).Conclusion:There was no significant correlation between the P and the clinical pregnancy rate on the fourth day after embryo transfer,however,the early spontaneous abortion rate was lower when the P between 50-120 nmol/L.