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目的:探讨原发性高血压患者和正常血压者脉压水平与冠状动脉病变相关性。方法:将553例行冠状动脉造影的患者分为原发性高血压(高血压)组和正常血压组,再根据冠状动脉造影结果将2组再分为冠心病组和非冠心病组2个亚组,分别比较2组冠心病和非冠心病亚组之间脉压的水平,并将高血压组和正常高血压组不同脉压水平的患者冠心病的发生率进行比较,以探讨高血压患者和血压正常者冠心病的发生率与脉压的相关性。结果:不论高血压组和正常血压组,其冠心病亚组与非冠心病亚组比较,冠心病亚组脉压明显高于非冠心病亚组(P<0.05);脉压≥40mmHg(1mmHg=0.133kPa)患者冠心病发生率明显高于脉压<40mmHg患者(P<0.05)。结论:不论是否伴发高血压,脉压是冠心病发展的一个重要的、独立的预测指标,是冠心病发生发展的独立的危险因素。
Objective: To investigate the relationship between pulse pressure and coronary artery disease in patients with essential hypertension and normotensive. Methods: 553 coronary angiography patients were divided into primary hypertension (hypertension) group and normotensive group. According to coronary angiography results, the two groups were further divided into two groups: coronary heart disease group and non-coronary heart disease group Subgroups to compare the levels of pulse pressure between two subgroups of coronary heart disease and non-coronary heart disease groups, and compare the incidence of coronary heart disease in patients with hypertension and normal hypertension with different pulse pressure levels to explore the relationship between hypertension Correlation between pulse pressure and incidence of coronary heart disease in patients and normotensives. Results: Compared with non-CHD subgroups, the pulse pressure in CHD subgroups was significantly higher than that in non-CHD subgroups (P <0.05) = 0.133kPa) patients with coronary heart disease was significantly higher than those with pulse pressure <40mmHg (P <0.05). CONCLUSION: Pulse pressure is an important and independent predictor of coronary heart disease, whether or not associated with hypertension, and is an independent risk factor for the development of coronary heart disease.