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目的:探讨尼莫地平联合奥拉西坦胶囊治疗老年血管性痴呆的临床疗效。方法:将本院收治的老年血管性痴呆患者分为对照组和治疗组,其中对照组给予奥拉西坦胶囊治疗,治疗组在对照组基础上给予尼莫地平口服,治疗一疗程后比较两组患者的临床疗效及不良反应情况。结果:对照组总有效率为83.02%,治疗组总有效率为96.23%,两组比较差异有统计学意义(P<0.05)。结论:尼莫地平联合奥拉西坦胶囊治疗老年血管性痴呆疗效确切,安全有效,副作用小,值得临床上推广应用。“,” Objective:To investigate the clinical efficacy of nimodipine combined with oxiracetam in treating the vascular dementia of elderly. Method:Vascular dementia of elderly were divided into a control group and a treatment group,and the control group was given oxiracetam capsule treatment,the treatment group was given nimodipine on the basis of the control group. The two groups were compared clinical efficacy and adverse reactions after a course. Result:The total effective rate of control group and treatment group was 83.02%and 96.23%,and the two groups had a significant difference(P<0.05). Conclusion:The clinical efficacy of nimodipine combined with oxiracetam in treating the vascular dementia of elderly is safe and effective,with little side effects,which is worthy of clinical application.