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目的观察雷公藤多苷对大鼠佐剂性关节炎(AA)黏膜免疫的影响。方法完全弗氏佐剂免疫大鼠,以雷公藤多苷治疗,观察大鼠黏膜免疫各项指标。结果雷公藤多苷可以改善AA大鼠病理改变,并调节AA大鼠的黏膜免疫功能。结论雷公藤多苷对AA模型大鼠有抗炎和免疫抑制作用。
Objective To observe the effects of Tripterygium glycosides on mucosal immunity in adjuvant arthritis (AA) rats. Methods Rats immunized with complete Freund’s adjuvant were treated with Tripterygium glycosides. The indexes of mucosal immunity in rats were observed. Results Tripterygium glycosides can improve the pathological changes of AA rats and regulate the mucosal immune function of AA rats. Conclusion Tripterygium glycoside has anti-inflammatory and immunosuppressive effects on AA model rats.