高血压病是一种慢性病,一旦确诊,需长期治疗。使用抗高血压药物约有10～50%的患者出现这样或那样的不良反应。现归纳如下: 一、体位性低血压和首剂效应某些药物抑制血管运动中枢,阻断压力感受器的反射弧或者直接扩张静脉,以至直立位时不能发生相应调节而致低血压。临床表现为头晕、眼花、心悸、出冷汗,严重时可发生晕厥,此即体位性低血压。抗高血压药物中肼苯哒嗪、胍乙啶,长压定 Hypertension is a chronic condition that, once diagnosed, requires long-term treatment. One or more of these adverse reactions occur in about 10% to 50% of patients taking antihypertensives. Now summarized as follows: First, orthostatic hypotension and the first dose of certain drugs inhibit the vasomotor center, blocking the baroreceptor reflex arc or direct dilatation of the vein, and upright position can not occur when the corresponding regulation and hypotension. Clinical manifestations of dizziness, vertigo, dizziness, heart palpitations, cold sweats, syncope may occur in severe cases, which is orthostatic hypotension. Antihypertensives hydralazine, guanethidine, long-pressure set