<正> Although glycogen synthase kinase-3(GSK-3)might act as a tumor suppressor since its inhibition is expected tomimic the activation of Wnt-signaling pathway,
<正> Autophagic and proteasomal proteolysis are two major pathways for degradation of cellular constituents.Currentmodels suggest that autophagy is responsible
Cancer cells show characteristic alterations in DNA methylation patterns. Aberrant CpG methylation of specific promoters results in inactivation of tumor suppre