论文部分内容阅读
目的:采用响应曲面法优化朱砂根中岩白菜素的最佳工艺条件。方法:在单因素的基础上运用Box-Behnken中心组合设计以提取时间、液固比和提取功率3因素3水平的试验模型,建立回归方程。采用响应曲面法对试验结果进行了分析,对朱砂根中岩白菜素的提取工艺条件进行优化。结果:模拟得到的最佳提取条件:提取时间为41.21 min,液固比为10.14∶1(m L·g~(-1)),提取功率为108.83 W,此时的最大提取率为2.233%。为了便于实际操作,修正条件为:提取时间42 min,液固比为10∶1(m L·g~(-1)),提取功率为109 W,验证试验结果平均提取率为2.318%,与模型预测值较为接近。结论:本文所建立的数学模型精度高(P<0.01),可对朱砂根中岩白菜素超声波提取工艺进行分析和预测。
Objective: To optimize the optimal process conditions of bergenin in cinnabar roots by response surface methodology. Methods: Based on the single factor, the Box-Behnken center combination design was used to extract the time, liquid-solid ratio and extraction power of 3 factors and 3 levels test model to establish the regression equation. The response surface method was used to analyze the test results to optimize the extraction conditions of bergenin in cinnabar root. Results: The optimal extraction conditions were as follows: the extraction time was 41.21 min, the liquid-solid ratio was 10.14:1 (m L · g -1), the extraction power was 108.83 W, and the maximum extraction rate at this time was 2.233% . For the sake of practical operation, the conditions for the extraction were as follows: the extraction time was 42 min, the liquid-solid ratio was 10:1 (m L · g -1), the extraction power was 109 W, and the average extraction rate was 2.318% The model predictive value is closer. Conclusion: The mathematical model established in this paper has high precision (P <0.01), which can be used to analyze and predict the ultrasonic extraction technology of bergenin in cinnabar roots.