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应用苯甲酸雌二醇和少量黄体酮肌肉注射复制大白鼠乳腺增生病模型的方法,观察了溶纤合剂对这种乳腺增生病模型的防治效果。结果表明,雌激素和少量黄体酮复制大白鼠乳腺增生病模型成功率高达100%,其病变与人类乳腺增生病基本一致;溶纤合剂对大白鼠乳腺增生病有明显的防(P<0.01)治(P<0.05)效果。
The method of intramuscular injection of estradiol benzoate and a small amount of progesterone was used to replicate the model of mammary gland hyperplasia in rats, and the effect of dissolution and dissolution of fibrinolytic agent on the mammary gland hyperplasia model was observed. The results showed that the success rate of estrogen and a small amount of progesterone in the replication of rat mammary gland hyperplasia model was as high as 100%, and the lesions were basically consistent with human hyperplasia of mammary glands; lysis fiber mixture had significant protection against mammary gland hyperplasia in rats (P<0.01). Treatment (P<0.05) effect.