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血清肿瘤标志物检测由于取材简便、方法易行并且在某些肿瘤发生之前就有表达,已成为人们诊断肿瘤早期的首选方法;由于单一的血清肿瘤标志物检测准确率不高,导致其在临床上的应用价值受到怀疑。近年来的研究发现,将几种血清肿瘤标志物联合使用可以提高其对肿瘤早期诊断的灵敏度和特异性。因此,寻找新的血清肿瘤标志物是目前肿瘤早期诊断的研究热点。本文综述了新发现的一些血清肿瘤标志物如CSTB、MKRN1、DKK-1、MSMB等及相关研究进展。
Detection of serum tumor markers due to simple material, the method is easy and has been expressed in some tumors, has become the preferred method of diagnosis of cancer early; as a single serum tumor markers detection accuracy is not high, leading to its clinical Application value on the subject of doubt. In recent years, the study found that the combination of several serum tumor markers can improve its sensitivity and specificity for early diagnosis of tumors. Therefore, looking for new serum tumor markers is currently a hot research topic in the early diagnosis of cancer. This article reviews some of the newly discovered serum tumor markers such as CSTB, MKRN1, DKK-1, MSMB and so on.