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美国的一般医疗单位采用短程化疗治疗肺结核进展相当缓慢,尽管通过细致的临床试验,已充分证明其优点。本文报告1976年1月至1982年12月,经细菌学证实的1,028例肺结核患者的治疗总结。患者年龄18~99(平均60.5)岁,59%大于60岁。痰涂片阳性的777例中,胸部X线片有空洞病灶者709例(69%);251例痰涂片阴性者中,有空洞病灶92例(9%)。治疗采用9个月疗程,首先异烟肼300mg、利福平600mg,每天1次,共1个月,随后用异烟肼900mg、利福平600mg,每周2次,再治疗8个月。患者
The progress made by general medical units in the United States for the treatment of tuberculosis by using short-course chemotherapy has been rather slow, although its merits have been fully demonstrated through careful clinical trials. This article reports the summary of the treatment of 1,028 tuberculosis confirmed bacteriologically from January 1976 to December 1982. Patients aged 18 to 99 (average 60.5) years old, 59% older than 60 years. Of the 777 positive sputum smears, 709 (69%) had chest lesions with empty lesions and 92 (9%) had empty lesions in 251 sputum smear-negative subjects. Treatment with a 9-month course of treatment, first isoniazid 300mg, rifampin 600mg, 1 day, a total of 1 month, followed by isoniazid 900mg, rifampicin 600mg, 2 times a week, and then treated for 8 months. patient