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疼痛是疾病的主要症状之一,是一种复杂的生理心理活动。头痛在临床颇为多见,病因往往难以查清,最近Caviness等将头痛病因归纳为血管性头痛和丛集性头痛。不管何种原因引起的头痛,很可能有着一定的共同神经化学基础。资料表明,许多神经系统的疾病与单胺类物质的代谢异常有关,与5一羟色胺(5-HT)和多巴胺(DA)的关系尤为密切。越来越多的报道认为,这些物质属神经调递质。有些研究还表明,5-HT和儿茶酚胺类物质与疼痛有关,并与吗啡镇痛、针刺镇
Pain is one of the main symptoms of the disease, is a complex physiological and psychological activity. Headache is quite common in clinical, the etiology is often difficult to find out, the recent Caviness and other causes of headache will be summarized as vascular headache and cluster headache. No matter what the cause of headaches, it is likely to have some common neurochemical basis. The data suggest that many diseases of the nervous system are associated with abnormal metabolism of monoamines and are particularly closely linked to 5-HT and dopamine (DA). More and more reports suggest that these substances are neurotransmitters. Some studies have also shown that 5-HT and catecholamines are pain-related and analgesic with morphine, acupuncture in the town