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目的探讨基底动脉尖综合征(TOBS)的临床特点。方法回顾性分析22例TOBS患者的临床资料。结果基底动脉尖综合征危险因素是高血压病、糖尿病、心脏病、高脂血症,既往脑卒中史、吸烟史、饮酒史等;脑栓塞是主要的病因;临床表现复杂多样,常见眩晕、眼球运动障碍、瞳孔异常、意识障碍、肢体瘫痪等;影像学特征多为双侧幕上、幕下多发梗死灶。病灶分布依次为:丘脑、中脑、枕叶、小脑等。治疗后22例死亡2例,恶化6例,有效9例,显效3例,治愈2例。结论TOBS预后差,病死率及致残率高,提高认识,重视危险因素的控制,早期诊断,早期治疗是关键。
Objective To investigate the clinical features of basilar artery syndrome (TOBS). Methods The clinical data of 22 patients with TOBS were retrospectively analyzed. Results The risk factors of basilar apical syndrome were hypertension, diabetes, heart disease, hyperlipidemia, previous stroke history, smoking history, drinking history, etc .; cerebral embolism was the main etiology; clinical manifestations were complex and varied, common dizziness, Eye movement disorders, pupillary abnormalities, unconsciousness, limb paralysis, etc .; imaging features mostly bilateral on the screen, infratemporal multiple infarction. Lesions distribution followed by: thalamus, midbrain, occipital lobe, cerebellum and so on. After treatment, 22 cases died of 2 cases, 6 cases were deteriorated, 9 cases were effective, 3 cases were cured and 2 cases were cured. Conclusion TOBS poor prognosis, mortality and morbidity, improve awareness, emphasis on risk factors control, early diagnosis, early treatment is the key.