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目的探讨心肌肌钙蛋白I(cTnI)对于不稳定型心绞痛和急性心肌梗死的诊断价值,为临床治疗提供参考。方法将高碑店市医院随机收集到的临床诊断为不稳定型心绞痛(80例)的病例作为观察组,无心血管疾病的健康者100例作为对照组,治疗前对两组检测的cTnI值进行比较,同时观察不稳定型心绞痛不同预后患者的cTnI值。结果在治疗前,观察组血cTnI水平明显高于对照组,两组比较差异有统计学意义(P<0.05)。经过治疗后,显效24例(30%),有效32例(40%),无效24例(30%),总有效率为72.0%。同时显效与有效患者的cTnI值明显小于无效患者(P<0.05)。结论 cTnI作为近年来发展起来的检测心肌损伤的高能指标,可以作为不稳定型心绞痛早期诊断的特异性指标,同时也可以作为其预后判断的标志,值得推广应用。
Objective To investigate the diagnostic value of cardiac troponin I (cTnI) in patients with unstable angina pectoris and acute myocardial infarction and provide reference for clinical treatment. Methods The cases of unstable angina pectoris (80 cases) were collected randomly from Gaobeidian City Hospital as observation group and 100 healthy people without cardiovascular disease as the control group. Before treatment, the cTnI values of the two groups were measured The cTnI values of patients with different prognosis of unstable angina pectoris were also observed. Results Before treatment, the level of cTnI in the observation group was significantly higher than that in the control group, with significant difference between the two groups (P <0.05). After treatment, effective in 24 cases (30%), effective in 32 cases (40%), ineffective in 24 cases (30%), the total effective rate was 72.0%. At the same time, the effective and effective patients cTnI value was significantly less than ineffective patients (P <0.05). Conclusion cTnI, as a high-energy index for detecting myocardial injury, developed in recent years, can be used as a specific indicator of early diagnosis of unstable angina pectoris and as a marker of prognosis. It is worth popularizing and applying.