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目的观察血必净注射液对脓毒症患者凝血功能的影响。方法将51例有凝血功能障碍的脓毒症病例随机分为两组,对照组给予常规综合治疗,治疗组加用血必净注射液治疗,疗程7 d。分别检测两组治疗前后凝血功能相关指标(血小板计数、凝血酶时间、凝血酶原时间、活化部分凝血活酶时间和纤维蛋白原)。结果治疗7 d后,治疗组患者凝血功能障碍明显好转,两组间比较,差异有统计学意义(P<0.05)。结论血必净注射液能有效改善脓毒症患者的凝血功能障碍。
Objective To observe the effect of Xuebijing injection on the coagulation function in patients with sepsis. Methods Seventy-one cases of sepsis with coagulation disorders were randomly divided into two groups. The control group was given conventional comprehensive treatment. The treatment group was treated with Xuebijing injection for 7 days. The indexes of coagulation function (platelet count, thrombin time, prothrombin time, activated partial thromboplastin time and fibrinogen) before and after treatment were detected. Results After 7 days of treatment, the coagulation dysfunction in the treatment group was significantly improved. There was significant difference between the two groups (P <0.05). Conclusion Xuebijing injection can effectively improve coagulation dysfunction in patients with sepsis.