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锑剂用於治疗血吸虫病始於1915年。距今虽已41年,然仍无疗效更高、而反应更少的化学合成品可以代替。故今日锑剂仍为治疗血吸虫病的主要药品。本文所谓锑剂系指三价锑。吾人常用者为酒石酸锑钾,其疗效可达60%—80%左右。其缺点为经治疗者仍有20%40%复发,且毒性很大,反应很多。有的反应,除增加病人痛苦外并不影响治疗。有的则极为严重,且可以致死。本文所谓反应包括一般中毒现象及某一器官受损害的症状。反应种类、程度及发生率常因时、地、病之类型、病人健康状况、年龄、营养、制剂、疗法、护理等而有所差别。目前各地正在进行大规模的血吸虫病防治工作,治疗乃为重要环节之一。参加治疗工作的人、对於锑剂反应及其处理具有一定知识
Antimony agent for the treatment of schistosomiasis began in 1915. Although 41 years ago, there is still no more effective and less reactive chemical synthesis products can be replaced. Antimony agents are still the main drugs for the treatment of schistosomiasis today. Antimony agent in this article means trivalent antimony. My common user is antimony potassium tartrate, its efficacy up to 60% -80%. The disadvantage is that the treatment is still 20% 40% recurrence, and the toxicity of a lot, a lot of reactions. Some reactions, in addition to increasing the patient’s suffering does not affect the treatment. Others are extremely serious and can be lethal. The so-called reaction includes the phenomenon of general poisoning and damage to an organ. The type, degree and incidence of the reaction often vary with time, place, disease type, patient’s health status, age, nutrition, preparation, therapy and nursing. At present, large-scale prevention and treatment of schistosomiasis is under way and treatment is one of the important links. People who participate in the treatment work have a certain knowledge of the antimony agent reaction and its treatment