患者,女,68岁,因脚趾红肿肿痛,多发水泡,行走困难,于2009年6月来我院皮肤科就诊。查体:双脚趾底均有多个椭圆形水泡,水泡壁厚,外清内黑,其中大脚趾下水泡已破,皮肤泛红,有渗出。整个大脚趾红肿剧烈疼痛,行走困难。双手指也有2个同样的水泡,手掌红肿,抓物困难。双上肢有许多大小 The patient, female, 68 years old, was inflamed, swollen and toe with multiple blisters and had difficulty walking. She came to our hospital dermatology clinic in June, 2009. Physical examination: both ends of the toe have multiple oval blisters, blister wall thickness, black outside the clearance, in which the big toe blisters have been broken, the skin flushing, exudation. The big toe has severe pain and swelling, difficulty walking. Two fingers also have the same two blisters, palpebral swelling, grasping difficulties. There are many sizes of upper extremities