地卡因是常用的表面麻醉剂 ,具有吸收快 ,麻醉效果迅速的特点 ,其毒性反应虽不多见 ,但一旦发生却有致命危险。我科近 2年在使用地卡因时曾发生毒性反应 2例 ,经抢救成功 ,现报告如下。1　临床资料例 1:患者 ,女 ,2 7岁 ,声嘶半年。间接喉镜下声门暴露不清楚 ,拟行纤维喉镜检查 Cocaine is a commonly used topical anesthetic and has the characteristics of rapid absorption and rapid anesthetic effect. Although its toxicity is rare, it is fatally dangerous in the event of its occurrence. 2 cases of toxic reactions occurred in the past 2 years when we used dexamethasone. After successful rescue, the report is as follows. 1 clinical data Example 1: patients, female, 27 years old, hoarseness six months. Indirect laryngoscopy glottic exposure is unclear, the proposed fiberoptic laryngoscopy