【摘 要】
：
Dear Editor,rnLifelong premature ejaculation (LPE) is a type of sexual dysfunction in males and has three characteristics: (1) an intravaginal ejaculatory latency time (IELT) of ≤1 min; (2) insufficient control over delaying ejaculation; and (3) negative
【机 构】
：
Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
论文部分内容阅读
Dear Editor,rnLifelong premature ejaculation (LPE) is a type of sexual dysfunction in males and has three characteristics: (1) an intravaginal ejaculatory latency time (IELT) of ≤1 min; (2) insufficient control over delaying ejaculation; and (3) negative personal consequences, such as distress, frustration, and/or the avoidance of sexual intimacy.1Its etiologies involve the 5-hydroxytryptamine (5-HT) system. The use of 5-HT transporter (5-HTT) blockers (e.g., selective serotonin reuptake inhibitors, SSRIs) was found to prevent the reuptake of 5-HT from the synaptic cleft into the presynaptic serotonergic neurons, which leads to increased extracellular 5-HT levels, thereby delaying ejaculation.
其他文献
Androgen receptor (AR)-mediated androgen action provides not only a classical pivotal role in male development and functions but also a recently proven role in female reproductive physiology.Splice variants of AR are reported to occur in various androgen-
Smoking is a well-known risk factor of reproductive health.However,the effect of paternal smoking on fertility has been less extensively examined.We conducted a cross-sectional study in a mountainous area of South-West China to assess the effect of male s
Dear Editor,rnInfertility is a major health problem affecting 10%–15% of couples seeking to have children, and a male factor can be identified in about half of these cases.1 Nonobstructive azoospermia is one of the causes of male infertility (10%), result
The sperm maturation and storage functions of the epididymis are important determinants of ejaculate quality,and perhaps provide an avenue to male contraception.In the last 50 years,the creation of epididymal fertility profiles in laboratory animals was f
The aim of this study was to ascertain whether some patients with psychogenic erectile dysfunction (PED) who chose psychotherapy spontaneously improved their sexual function immediately after diagnosis. Two hundred eighty?ifve patients with PED were retro
Erectile dysfunction (ED) is considered a condition with a broad range of etiologies.Obstructive sleep apnea (OSA) syndrome is one of the lesser studied risk factors for ED.We intend to summarize the current evidence on the relationship between OSA and se
Wre summarize and comment on the topics discussed by the contributors to this Special Issue of Asian Journal of Andrology.The scope of varicocele covers a wide spectrum,including proteomics and metabolomics,hormonal control,interventional therapy,and assi
Prostate cancer is the second most common male cancer, with half of all patients going on to develop metastases. To better identify patients at high risk for prostate cancer progression and reduce prostate cancer?related mortality, improved prognostic fac
Erectile dysfunction (ED) in men under the age of 40 was once thought to be entirely psychogenic. Over the last few decades, advances in our understanding of erectile physiology and improvements in diagnostic testing have restructured our understanding of