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1.中草药片剂的制备方法与化学药品片剂的制备方法不完全相同,片重计算怎样进行?答:对于大多数有效成分不明的中草药片剂,因无法测定其有效成分的含量,片重计算方法就与化学药品片剂有所不同。如:可根据单服颗粒重或根据原药材服用量及药材提取后所得浸膏重来计算片重;也可以浸膏中总固体重及原粉重来计算片重。但其中对于某些已经提得有效成分并能进行含量测定的,片重计算方法仍与一般化学药品相同。由于在片剂的制备过程中添加了辅料,又经过制粒、烘干等一系列操作,加上这些操作中不可避免的各种损耗,为保证片剂的含量准确,在压片前应根据颗粒中药物的实际含量计算。方法与一般化学药品片剂相同。即:片重=每片颗粒重+临压片前平均每片加入辅料重=(每片所含药物量)/(颗粒测得的药物百分含量)+压片前平均每片加入辅料重若颗粒中药物的含量测定在加入各种辅料后进行,则每片的颗粒重即为片重。
1. Preparation of Chinese herbal tablets and chemical tablets preparation methods are not exactly the same, how to calculate tablet weight? A: For most of the active ingredients of unknown herbal tablets, because of its inability to determine the content of active ingredients, weight The calculation method is different from the chemical tablet. Such as: According to the weight of a single serving or according to the amount of raw herbs and herbs extracted extract weight again to calculate weight; also extract the total solids and original weight to calculate the weight of tablets. However, some of them have been mentioned for the active ingredient and can be content determination, weight calculation method is still the same as the general chemical drugs. Due to the addition of excipients in the preparation of tablets, but also through a series of operations such as granulation, drying, coupled with the inevitable loss of these operations, in order to ensure the content of tablets accurate before the tablet should be based on Calculation of the actual content of the drug in the granules. Methods and general chemical tablets the same. Namely: tablet weight = weight of each tablet + the average weight of each tablet prior to tabletting = (drug content per tablet) / (percentage of drug measured by the tablet) + average weight of each tablet before tabletting If the particles in the determination of the drug content after the addition of various excipients, then the weight of each piece is the tablet weight.