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我院于1988～1989年对11例重症角膜外伤患者在常规手术处理后,分别于不同时期滴用还原型谷胱甘肽,结果发现11例中凡在角膜基质层愈合进程中滴用该药液者所形成的瘢痕混浊范围和程度较角膜实质层创口基本愈合后才予滴药者为轻。 Hormann,Moses曾对牛眼中的还原型谷胱甘肽进行过定性和定量测定,结果证实了牛眼角膜组织中含有该成分约为16mg。动物实验提示其对角膜损伤群的活性最强烈。完整的角膜构成了脂肪-水-脂肪三重栅栏样生物膜屏障,局部所滴用的药液必需具有双相溶解度,才能穿透角膜。而当角膜上皮缺损时,增加了药物的
In our hospital from 1988 to 1989, 11 patients with severe corneal trauma after routine surgery, respectively, at different times drip with reduced glutathione, found in 11 cases of corneal stromal healing process in the drop of the drug Liquid who formed the scope of scarring and degree of corneal wound than the basic healing after the drop was only those who were light. Hormann, Moses had qualitative and quantitative determination of reduced glutathione in bovine eyes, the results confirmed that bovine corneal tissue contains about 16mg of the composition. Animal experiments suggest that its most corneal damage group activity. The intact cornea constitutes a fat-water-fat triple barrier-like biofilm barrier, and the locally applied drops must have biphasic solubility to penetrate the cornea. When the corneal epithelium defects, increased the drug’s