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我院自1978年初开始,采用中药当归、黄芪、酸枣仁、首乌等制成合剂,定命为“脑灵糖浆”,试验152例,取得较好的疗效,现总结如下: 药物简介一、脑灵糖浆的组方及制剂:当归、白芍、黄芪、、怀牛膝各450克,酸枣仁、茯苓各600克,丹参、首乌各750克,远志、石菖蒲各300克。用稀醇及50％乙醇先后浸泡2次,每次历时1周,取浸出液加稀醇至40％浓度备作。应用时再加单糖浆稀释至20％浓度。二、动物试验: 1.毒性试验小鼠腹腔内注射的粗略LD_(50)为4.5毫升/公斤体重。 2.协同戊巴比妥钠睡眠时间: 对照组小鼠10只,腹腔注射戊巴比妥钠
Since the beginning of 1978, our hospital has used a combination of Chinese angelica root, astragalus root, Suanzaoren, Shouwu, etc., and it will be ordered as “Naoling syrup”. 152 cases were tested and achieved better results. The results are summarized as follows: The formulation and preparation of Lingshen syrup: 450 grams of Angelica sinensis, Radix Paeoniae Alba, Radix Astragali, and Achyranthes bidentata, 600 grams of Semen Zizi and Radix Astragali, 750 grams of Radix Salviae Militiorrhiza, Radix Scutellariae, and 300 grams of Polygala tenuifolia and Radix Astragali. With dilute alcohol and 50% ethanol soaked 2 times, each time for 1 week, take leachate plus dilute alcohol to 40% concentration for preparation. When applied, add a single syrup to dilute to 20% concentration. Second, animal experiments: 1. Toxicity test The intraperitoneal injection of crude mice LD_ (50) was 4.5 ml/kg body weight. 2. Coordination with sodium pentobarbital sleep time: 10 mice in the control group were injected intraperitoneally with sodium pentobarbital