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目的观察联合吸入噻托溴铵及沙美特罗丙酸氟替卡松治疗慢性阻塞性肺疾病患者的临床效果。方法 100例慢性阻塞性肺疾病患者,随机分成对照组和观察组,每组50例,对照组患者给予单一的噻托溴铵干粉剂吸入法进行治疗,观察组患者在此基础上加用沙美特罗丙酸氟替卡松吸入进行治疗;所有患者治疗3个月为1个疗程,治疗后观察两组患者血气情况及肺功能恢复情况。结果治疗后,观察组患者在肺功能指标及血气指标上均优于对照组,差异具有统计学意义(P<0.05)。结论采取联合吸入噻托溴铵、沙美特罗丙酸氟替卡松治疗慢性阻塞性肺疾病具有更理想的临床效果,可明显改善患者血气情况及肺功能,有效的控制慢性阻塞性肺疾病的恶化,具有极高的临床价值。
Objective To observe the clinical effect of combined inhalation of tiotropium and fluticasone salmeterol in patients with chronic obstructive pulmonary disease. Methods One hundred patients with chronic obstructive pulmonary disease were randomly divided into control group and observation group, 50 cases in each group. Patients in control group were treated with a single inhalation of Tiotropium bromide powder. Patients in observation group were given Salmeterol Treatment with fluticasone trospirenone for treatment; all patients treated for 3 months as a course of treatment, after treatment, blood gas and lung function recovery were observed. Results After treatment, the patients in the observation group were better than the control group in the indexes of pulmonary function and blood gas, the difference was statistically significant (P <0.05). Conclusion Combined inhalation of tiotropium and salmeterol fluticasone propionate in the treatment of chronic obstructive pulmonary disease has a more ideal clinical effect, can significantly improve the patient’s blood gas and lung function, effectively control the deterioration of chronic obstructive pulmonary disease, with High clinical value.