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本文对青霉素 G 钾的溶血性进行了考察。体外实验表明:高浓度的青霉素 G 钾可造成溶血,且浓度越高,溶血现象越严重。在家兔体内,用测定尿胆素元的方法观察有无溶血现象的发生,结果表明:当以成人剂量48万u/kg/日给药时,也没有明显的溶血现象。
This article investigated the hemolytic properties of penicillin G potassium. In vitro experiments show that: high concentrations of penicillin G potassium can cause hemolysis, and the higher the concentration, the more serious hemolysis. In rabbits, hemolysis was observed by the method of determination of urobilinogen. The results showed that there was no obvious hemolysis when administered at an adult dose of 480,000 u / kg / day.