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钩吻是《本经》中一味著名的有毒中药。它的别名有野葛(《本经》)、秦钩吻、毒根(《吴普本草》)、冶葛、胡蔓草(《南方草本状》),黄野葛(《千金方》)、吻莽、断肠草(《梦溪笔谈》),黄藤、烂肠草(《本草纲目》),虎粮草(《岭南采药录》),大鸡苦蔓(《南方主要有毒植物》)等。我国植物分类学家多认为它是马钱科植物胡蔓藤Gelsemjum elegansBenth分布于我国南方。早在1931年赵承嘏等曾发表多篇论文报导从植物钩吻中提得生物碱而闻名国内外。同年候祥川等报导了钩吻素的药理作用,证明其毒性很高。从三十年代至
Hook kiss is a famous poisonous Chinese medicine in the “Ben Jing.” Its aliases include Kudzu (“The Classic”), Qin hook kiss, poison root (“Wu Pu’s Herbal”), Ye Ge, Hu Mancao (“Southern Herbal”), Huang Kui Ge (“Qian Jin Fang”), kiss Grasshoppers, Gracilaria (“Mengxi Bi Tan”), Yellow Rattan, Rotten Grass (“Compendium of Materia Medica”), Tiger Grass (“Lingnan Medicinal Herb Record”), Big Chicken bitter vine (“Southern poisonous plants”) and so on. Many plant taxonomists in China think that it is the plant of the Ranunculaceae genus Gelsemjum elegans Benth distributed in southern China. As early as 1931, Zhao Chengji and others had published many papers and reported that they obtained alkaloids from the plant hookfish and are well known at home and abroad. In the same year, Xiang Xiangchuan et al. reported on the pharmacological effects of ghrelin, demonstrating its high toxicity. From the 1930s to