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用全反式视黄酸(ATRA)处理3株胃癌细胞株MGC803、BGC823和SGC7901(ATRA终浓度为10－6MOL/L)连续20D,再移植于6~8周龄的BALB/C裸小鼠后肢皮下,观察移植瘤生长情况,4周后处死裸小鼠,解剖肿瘤并行组织学检查.结果表明,ATRA体外处理胃癌细胞能延长其移植瘤的潜伏期和倍增时间,有效地抑制移植瘤的生长,抑制率分别为51.4％、66.0％和88.6％,抑制作用的强弱次序与移植瘤的恶性程度正好相反.“,”お?o investigate the effects of alltrans retinoic acid (ATRA) on the growth of gastric cancer cells in nude mouse xenografts,three gastric cancer cell lines,MGc803,BGC823 and SGC7901,were treated with 10??-6? mol/L ATRA for 20d,and then inoculated subcutaneously in the right hind legs of nude mice respectively,while the untreated ones in the left hind legs.Four weeks after the implantation,the nude mice were executed,the xenografts were removed and examined pathologically.The results showed that the incubati...