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目的分析血清乙肝五项不同表达模式原发性肝癌(HCC)R0切除术患者的预后。方法 343例HBV相关HCC均行R0切除术,分析其血清乙肝五项表达模式与预后的关系。结果小三阳(HBsAg、HBeAb、HBcAb阳性)、1+5阳性(HBsAg、HBcAb阳性)、大三阳(HBsAg、HBeAg、HBcAb阳性)、其他模式患者的总生存期(OS)分别为69.0、27.9、84.0、72.0个月,无瘤生存期(DFS)分别为32.2、17.8、84.0、42.0个月。血清乙肝五项不同表达模式患者的OS、DFS比较,P均<0.05。结论血清乙肝五项不同表达模式HCC R0切除术患者的预后不同,其中以HBsAg、HBeAb阳性者预后最差。
Objective To analyze the prognosis of patients with Rho resection of primary hepatocellular carcinoma (HCC) with five different expression patterns of hepatitis B virus. Methods 343 cases of HBV-related HCC were performed R0 resection, analysis of the relationship between the five expression patterns of serum hepatitis B and prognosis. Results The overall survival (OS) of three positives (HBsAg, HBeAb and HBcAb positive), 1 + 5 positive (HBsAg and HBcAb positive) and HBsAg positive (HBsAg, HBeAg and HBcAb positive) were 69.0 and 27.9 , 84.0,72.0 months, disease-free survival (DFS) were 32.2,17.8,84.0,42.0 months. Serum HBV in five different expression patterns of OS, DFS, P <0.05. Conclusions The prognosis of patients with HCC R0 resection with different expression patterns of five hepatitis B patients is different, among which HBsAg and HBeAb positive patients have the worst prognosis.