目的探讨影响急性外伤性硬脑膜外血肿疗效的相关因素。方法对1994年5月至2004年5月收治的484例外伤性硬脑膜外血肿患者的临床资料进行回顾性分析。结果无脑疝症状者手术死亡率7.7%,有脑疝症状者死亡率21.3%。手术距脑疝发生时间<1h死亡率8.2%,1～2h死亡率40.0%,>2h死亡率72.2%。结论影响外伤性硬脑膜外血肿疗效的相关因素较多,除脑疝形成及手术距脑疝发生的时间外,创伤性低血压、合并脑损伤的程度、呼吸功能不全、大面积脑梗塞、血糖与血浆渗透压升高及肝功能异常等均对患者预后有重要影响。 Objective To explore the related factors that affect the efficacy of acute traumatic epidural hematomas. Methods The clinical data of 484 patients with traumatic epidural hematomas admitted from May 1994 to May 2004 were analyzed retrospectively. Results No hernia symptoms of surgical mortality 7.7%, with hernia symptoms 21.3% mortality. Operation from the time of hernia <1h 8.2% mortality, 1 ~ 2h 40.0% mortality,> 2h mortality 72.2%. Conclusion There are many related factors that affect the curative effect of traumatic epidural hematoma. In addition to the time of hernia formation and operation from traumatic hernia, traumatic hypotension, the degree of brain injury, respiratory insufficiency, large area cerebral infarction, blood glucose And the increase of plasma osmotic pressure and abnormal liver function have a significant impact on the prognosis of patients.