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随着技术水平提高和花费降低,逐渐增多的基因测序使得基因治疗成为可能。展望未来,人的基因可以引导疾病治疗决策来优化疗效及减少不良反应。已知人的遗传易感性可帮助在某些特定疾病发生前确立一级预防策略。基因筛查获益的可预防疾病包括2型糖尿病(T2DM),它的发病包含遗传和环境因素,体重减轻和药物(如二甲双胍)可以阻
As technology advances and costs go down, increasing gene sequencing has made gene therapy possible. Looking ahead, human genes can guide disease treatment decisions to optimize efficacy and reduce adverse reactions. The genetic susceptibility of humans is known to help establish a primary prevention strategy before the onset of certain diseases. Preventive diseases benefiting from genetic screening include type 2 diabetes mellitus (T2DM), whose morbidity includes genetic and environmental factors, weight loss and medication (such as metformin) can block