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目的:探讨昆山地区受教育程度与静坐时间交互作用对身体活动不足的影响。方法:采用多阶段整群随机抽样方法，于2016年对江苏省昆山市18~69岁常住居民进行问卷调查与体格检查并获得身体活动水平。多因素logistic回归分析诸因素与身体活动不足的关联；采用交互作用指数（S）、交互作用相对超额危险度（RERI）及归因危险度（AP）评价相加交互作用。结果:工作及家务体力活动率10.23%，交通体力活动率为41.84%，经常锻炼率为28.98%。总人群、男性及女性人群身体活动不足分别为50.66%（95%n CI：49.04%~52.28%）、52.29%（95%n CI：49.94%~54.64%）和49.29%（95%n CI：47.06%~51.52%）。多因素Logistic回归模型分析显示，高腰臀比（n OR=1.12，95%n CI：1.02~1.23），无高血压家族史（n OR=1.24，95%n CI：1.14~1.36）、新诊断糖尿病（n OR=1.35，95%n CI：1.09~1.68）、既往诊断糖尿病（n OR=1.34，95%n CI：1.07~1.69）、知晓自己腰围（n OR=1.34，95%n CI：1.21~1.48）及高密度脂蛋白偏低（n OR=1.14，95%n CI：1.03~1.27）与身体活动不足之间的关联有统计学意义。不仅较高教育程度（n OR=1.27，95%n CI：1.10~1.46）和较长静坐时间（n OR=1.37，95%n CI：1.20~1.57）与身体活动不足存在关联，而且身体活动不足归因于两者的比例占18.3%［基于n OR尺度的RERI=0.367，95%n CI：0.105~0.629；AP=0.183，95%n CI：0.060~0.306、S=1.572，95%n CI：1.079~2.289］。n 结论:较高教育程度和较长静坐时间是昆山地区18~69岁人群身体活动不足的重要共同影响因素。“,”Objective:To explore the joint association of education attainment and sedentary with insufficient physical activity in Kunshan, Jiangsu province.Methods:Multi-stage cluster random sampling method was conducted in 2016 in Kunshan City, physical activity levels were collected according to structure questionnaire, and multivariate logistic regression was used to identify factors associated with physical activity level. Logistic model was used to estimate interaction effect by the synergy index (S), the relative excess risk of interaction (RERI) and the attributable proportion due to interaction (AP).Results:Housework, traffic and regular exercise physical activity accounted for 10.23%, 41.84%, and 28.98%, respectively. Insufficient physical activity in total, male, and female population were 50.66% (95%n CI: 49.04%-52.28%), 52.29% (95%n CI: 49.94%-54.64%), and 49.29% (95%n CI: 47.06%-51.52%). Multivariable logistic regression analysis demonstrated that high waist to hip ratio (n OR=1.12, 95%n CI: 1.02-1.23), free of family history of hypertension (n OR=1.24, 95%n CI: 1.14-1.36), newly diagnosed diabetes (n OR=1.35, 95%n CI: 1.09-1.68), previously diagnosed diabetes (n OR=1.34, 95%n CI: 1.07-1.69), awareness of waist (n OR=1.34, 95%n CI: 1.21-1.48), and lower level of high density lipoprotein (n OR=1.14, 95%n CI: 1.03-1.27) were positively correlated with insufficient physical activity. Moreover, high educational attainment (n OR=1.27, 95%n CI: 1.10-1.46) and sedentary duration (n OR=1.37, 95%n CI: 1.20-1.57) were associated with insufficient physical activity, and additive interaction was found between two factors on insufficient physical activity (RERI=0.367, 95%n CI: 0.105-0.629. AP=0.183, 95%n CI: 0.060-0.306. S=1.572, 95%n CI: 1.079-2.289).n Conclusion:Among permanent residents whose age between 18-69 years in Kunshan, insufficient physical activity is more prevalent, high education and sedentary are jointly associated with insufficient physical activity.