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目的探讨氨溴索雾化吸入治疗矽肺合并肺部感染的临床疗效。方法 100例矽肺合并肺部感染患者,随机分为治疗组和对照组,各50例,均予以抗感染及对症处理,治疗组在此基础上加用氨溴索雾化吸入治疗。比较两组治疗后的临床疗效。结果治疗组在总有效率、肺功能改善和提高血氧分压方面都明显优于对照组(P<0.05)。结论氨溴索雾化吸入有利于排出呼吸道分泌物,能有效改善矽肺合并肺部感染的症状和体征,改善通气功能并缩短疗程。疗效确切,未发现明显毒副作用。
Objective To investigate the clinical efficacy of ambroxol inhalation in the treatment of silicosis complicated with pulmonary infection. Methods One hundred patients with silicosis and pulmonary infection were randomly divided into treatment group and control group, with 50 cases in each group. All patients were given anti-infective and symptomatic treatment. The treatment group was treated with ambroxol inhalation. The clinical efficacy of the two groups after treatment was compared. Results The treatment group was significantly better than the control group (P <0.05) in terms of total effective rate, improvement of pulmonary function and improvement of partial pressure of oxygen. Conclusion Inhaled inhalation of ambroxol is conducive to the discharge of respiratory secretions, can effectively improve the symptoms and signs of silicosis complicated with pulmonary infection, improve ventilation and shorten the course of treatment. The exact effect, no significant side effects were found.