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目的探讨膀胱嗜铬细胞瘤的诊断及治疗。方法本组5例膀胱嗜铬细胞瘤患者,男性2例,女性3例,其中1例为术后复发病例,有高血压症状者4例,排尿后血压增高患者2例。3例行血儿茶酚氨检查,均为阳性。5例均行CT定位诊断。结果果5例膀胱嗜铬细胞瘤,3例位于膀胱右后壁,1例位于后壁,1例位于前壁。1例放弃治疗,4例行膀胱部分切除术,其中1例行腹腔镜下膀胱部分切除术。术中收缩压上升大于30mmHg者2例,术中平均出血量150(100~200)ml,平均手术时间153(121~183)min。恶性3例,良性2例,术后随访7个月~4年。术后2例复发,1例全身多发转移,其中2例死亡。结论膀胱嗜铬细胞瘤罕见且容易误诊,高血压为其主要症状,排尿后血压增高为其特征性表现。膀胱部分切除术安全、有效。术后有复发可能,应密切随访。
Objective To investigate the diagnosis and treatment of bladder pheochromocytoma. Methods In this group of 5 patients with bladder pheochromocytoma, there were 2 males and 3 females. Among them, 1 case was postoperative recurrence, 4 cases had hypertension, and 2 cases had urinary hypertension. 3 cases of blood catechin ammonia test, were positive. 5 cases were diagnosed by CT. Results Five cases of bladder pheochromocytoma, three in the right posterior wall of the bladder, one in the posterior wall, and one in the anterior wall. 1 case gave up treatment, 4 cases undergone partial resection of the bladder, including 1 case of laparoscopic partial cystectomy. Intraoperative systolic blood pressure increased more than 30mmHg in 2 cases, intraoperative blood loss of 150 (100 ~ 200) ml, the average operation time 153 (121 ~ 183) min. Malignant in 3 cases, benign in 2 cases, followed up for 7 months to 4 years. Two patients relapsed after operation, and one patient had systemic multiple metastasis. Two of them died. Conclusions Bladder pheochromocytoma is a rare and easily misdiagnosed disease. Hypertension is the main symptom and the characteristic blood pressure increases after urination. Partial bladder resection is safe and effective. Postoperative recurrence may be close follow-up.