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目的:对2008年10月1日~2012年9月30日皖北地区蚌埠、阜阳、亳州3市新生儿先天性甲状腺功能减低症筛查的情况进行分析和总结,了解皖北地区先天性甲状腺功能状减低症的筛查情况和发病率。方法:采用干血滤纸片法,测定新生儿促甲状腺素(TSH)浓度,筛查阳性患儿继续测定血清中游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)及TSH做出诊断。结果:4年来共筛查378 419例新生儿,确诊先天性甲低患儿144例,发病率为1/2 628。结论:新生儿疾病筛查能够早期识别CH患儿,并使之得到早期诊治,是提高出生人口素质的重要措施。
OBJECTIVE: To analyze and summarize the screening of congenital hypothyroidism (Hypothyroidism) in neonates in Bengbu, Fuyang and Bozhou of northern part of Anhui Province from October 1, 2008 to September 30, 2012 to understand the congenital thyroid Functional reduction in the screening of the disease and the incidence. Methods: The serum TSH concentrations were determined by dry blood filter paper method. The serum levels of free triiodothyronine (FT3), free thyroxine (FT4) and TSH were determined by screening positive children diagnosis. Results: A total of 378 419 newborns were screened in 4 years and 144 cases of congenital hypothyroidism were diagnosed with a prevalence of 1/2 628. Conclusion: Neonatal screening can identify CH children early and get early diagnosis and treatment, which is an important measure to improve the quality of birth population.