Velocity field of evaporating liquid film in a wiped molecular distillator was simulated with a computational fluid dynamics (CFD) software, and two turbulent models treating near-wall flow were compared. Differences between wiped and other molecular distillations were intro-duced to explain why turbulent model should be used in this simulation. Three assumptions were made in order to simplify simulating processes. In rotating coordinate system, fixed other settings, the above two turbulent models were used, and the volume of fluid (VOF) multiphase model was also applied to tracking the liquid-gas surface. Both of the simulating results are basically iden-tical with real situation and were compared in several aspects. It was concluded that both of the turbulent models are suitable in this simulation. Velocity field of evaporating liquid film in a wiped molecular distillator was simulated with a computational fluid dynamics (CFD) software, and two turbulent models treating near-wall flow were compared. Differences between wiped and other molecular distillations were intro-duced to explain why turbulent Three rotating conditions system, fixed other settings, the above two turbulent models were used, and the volume of fluid (VOF) multiphase model was also applied to Both the the simulating results are basically iden-tical with real situation and were compared in several aspects. It was verified that both of the turbulent models are suitable in this simulation.