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特发性真性性早熟以女性多见。现将我院所见2例男性和4例女性患者报告如下,并结合文献加以讨论。例1 男就诊年龄4.5岁,住院号14436。患儿足月顺产,母乳喂养。2.5岁起外生殖器明显增大,3.5岁时已达成人大小,有阴毛生长,语音变粗。无头颅外伤史和家族史。体检:身高118cm(正常同龄儿童平均身高100cm),肩宽,胸大肌发达。心肺正常,肝脾未及。阴茎、睾丸似成人大小,有少量阴毛生长。皮肤无色素沉着。实验室检查:肝功正常,血糖6.72mmol/L(121mg/dl,胆固醇1.52mmol/L(58.5mg/dl),血钾、钠、氯化物正常,钙5mmol/L(10mg
Idiopathic sexual precocity is more common in women. Now we see 2 cases of male and 4 female patients reported as follows, combined with the literature to be discussed. Example 1 Male patient age 4.5 years, hospital number 14436. Children with full term delivery, breastfeeding. 2.5 years old genitalia significantly increased, reached the age of 3.5 adult size, pubic hair growth, voice thick. No history of head trauma and family history. Physical examination: height 118cm (normal children of the same age average height 100cm), shoulder width, pectoralis major developed. Cardiopulmonary normal, liver and spleen not yet. Penis, testis-like adult size, a small amount of pubic hair growth. Skin pigmentation. Laboratory tests: normal liver function, blood glucose 6.72mmol / L (121mg / dl, cholesterol 1.52mmol / L (58.5mg / dl), potassium, sodium, chloride normal calcium 5mmol / L