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目的观察全自动呼吸机(Auto-CPAP)治疗对脑梗死急性期合并OSAHS患者血脂及hs-CRP的影响。方法选择脑梗死急性期合并OSAHS患者100例,随机分为Auto-CPAP治疗组50例和对照组50例,对照组采用常规神经内科治疗,治疗组在常规治疗基础上采用呼吸机治疗4周,比较治疗4周前后血脂及hs-CRP的变化情况。结果治疗组及对照组血脂均较治疗前下降(P<0.05),经Auto-CPAP治疗后4周胆固醇(TC)及低密度脂蛋白胆固醇(LDL-C)下降优于对照组(P<0.05),2组患者血浆超敏C反应蛋白(hs-CRP)均较治疗前明显下降(P<0.05)。结论Auto-CPAP治疗可改善脑梗死急性期合并OSAHS患者血脂及hs-CRP。
Objective To observe the effect of automatic ventilator (Auto-CPAP) on blood lipids and hs-CRP in patients with acute cerebral infarction complicated with OSAHS. Methods One hundred patients with acute cerebral infarction complicated with OSAHS were randomly divided into 50 cases in Auto-CPAP group and 50 cases in control group. The control group was treated by conventional neurology. The treatment group was treated with ventilator for 4 weeks on the basis of routine treatment, Compare the changes of blood lipid and hs-CRP before and after treatment for 4 weeks. Results The levels of TC and LDL-C decreased 4 weeks after Auto-CPAP treatment in the treatment group and the control group compared with the control group (P <0.05) ), And plasma hs-CRP levels in two groups were significantly lower than those before treatment (P <0.05). Conclusion Auto-CPAP can improve blood lipids and hs-CRP in patients with acute cerebral infarction complicated with OSAHS.