切口部位皮肤消毒是建立无菌手术野的第一步。无菌手术野的最薄弱环节是皮肤本身,尽管有各种消毒方法,但彻底灭菌是不大可能的。残留于皮肤的细菌会污染切口,引起切口感染。作者在178例胸、腹部手术病人中比较了以下三种皮肤消毒法:1.碘咐刷洗5分钟,再涂擦一遍碘咐,复盖消毒巾;2.碘咐刷洗5分钟,擦洗一遍酒精,复盖抗微生物薄膜;3.酒精擦洗1分钟,酒精蒸发后立即复盖抗微生物薄膜。所用抗微生物薄膜为碘咐和粘合剂混合浸制的手术巾。采用半定量细菌学分析法评价了各方法的灭菌效果。消毒前和缝合皮肤时细菌计数比较显示,三组皮肤消毒法都有明显的杀菌作用,并且效力近于相等,无统计学意义。单就碘咐刷洗5分钟、碘咐刷洗5分钟加酒精擦洗一遍和酒精擦洗1分钟的迅速杀菌作用比较,酒精擦洗1分钟作用最强,细菌计数分别为log_(10)~(0.97±0.10),log_(10)~(0.19±0.06)和log_(10)~(0.11±0.04)菌落/平 Skin incision site disinfection is to establish a sterile surgical field the first step. Sterile surgical field is the weakest link in the skin itself, despite a variety of sterilization methods, but complete sterilization is not possible. Bacteria that remains on the skin can contaminate the incision and cause incisional infection. The author in 178 cases of thoracic and abdominal surgery patients compared the following three kinds of skin disinfection method: 1. iodine scrub brushing for 5 minutes, and then wipe it again iodine, covering the disinfection towel; 2. iodine scrub for 5 minutes, scrub alcohol again , Covered with anti-microbial film; 3 alcohol scrub 1 minute, alcohol immediately after the cover anti-microbial film. The antimicrobial film used was a surgical towel mixed with iodine and an adhesive. The sterilizing effect of each method was evaluated by semi-quantitative bacteriological analysis. Bacterial counts before and during suturing showed that the three groups of skin disinfection had obvious bactericidal effect, and the efficacy was nearly equal, with no statistical significance. Single iodine scrub for 5 minutes, iodine scrub for 5 minutes plus alcohol scrub again alcohol scrub 1 minute compared to the rapid bactericidal effect of alcohol scrub 1 minute strongest role, the bacterial count were log_ (10) ~ (0.97 ± 0.10) , log_ (10) ~ (0.19 ± 0.06) and log_ (10) ~ (0.11 ± 0.04)