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目的:探讨早产孕妇母血C-反应蛋白(CRP)与早产胎膜早破、亚临床绒毛膜羊膜炎的关系。方法:回顾性分析84例早产孕妇的临床资料,采用数率散射比浊法检测其血清CRP水平,进行比较分析。结果:58例(69%)在早产临产前出现胎膜早破,其血清CRP水平高于无胎膜早破组,差异有统计学意义(11.7vs±3.4vs,9.2±1.3,P<0.05)。31例(36.9%)诊断为亚临床绒毛膜羊膜炎,其血清CRP水平高于无亚临床绒毛膜羊膜炎组,差异有统计学意义(14.1vs±2.6vs,8.5±1.4,P<0.05)。结论:监测孕妇血清CRP的浓度变化,有助于亚临床型绒毛膜羊膜炎的早期诊治。
Objective: To investigate the relationship between maternal serum C-reactive protein (CRP) and preterm premature rupture of membranes and subclinical chorioamnionitis in preterm labor. Methods: The clinical data of 84 pregnant women with preterm birth were retrospectively analyzed. The serum CRP levels were detected by the rate nephelometry. The comparative analysis was made. Results: 58 cases (69%) had premature rupture of membranes in preterm labor and their serum CRP levels were higher than those without premature rupture of membranes (11.7 vs ± 3.4 vs. 9.2 ± 1.3, P <0.05) ). 31 cases (36.9%) were diagnosed as subclinical chorioamnionitis with higher serum CRP level than those without subclinical chorioamnionitis (14.1 vs ± 2.6 vs 8.5 ± 1.4, P <0.05) . Conclusion: It is helpful for the early diagnosis and treatment of subclinical chorioamnionitis to monitor the concentration of serum CRP in pregnant women.